In overweight patients with non-alcoholic fatty liver disease Saroglitazar is able to improve transaminases but not liver stiffness measurement and controlled attenuation parameter unless accompanied by weight reduction
EASL LiverTree™, Prateek Padole, 226714
Influence of Hypothyroidism on Insulin Resistance and Adipokine Profile in Patients with Nonalcoholic Fatty Liver Disease
EASL LiverTree™, Vasyl PRYSYAZHNYUK, 226715
RNase MCPIP1 regulates hepatic PPAR gamma via TXNIP/PGC 1-alpha pathway
EASL LiverTree™, Natalia PYDYN, 226716
Insulin secretion is directly related to NASH, fibrogenesis and fibrosis in Non-diabetic patients with Non-Alcoholic Fatty Liver Disease
EASL LiverTree™, Chiara Rosso, 226717
Round-table discussion & Consensus Statement III: How should we manage patients with NAFLD/NASH in 2018? What lifestyle advice should we give?
EASL LiverTree™, Faculty / Presenter(s), 231716
Consideration of metabolic surgery and metabolic endoscopy?
EASL LiverTree™, Sigal Fishman, 227265
Clinical Case IV - illustration of evolution of case to cirrhosis to include T2DM and rising weight
EASL LiverTree™, Elisabetta BUGIANESI, 227264
Lifestyle management including nutrition and exercise
EASL LiverTree™, Mathias Plauth, 227263
Clinical Case III - case showing evolution to confirmed NASH
EASL LiverTree™, Elisabetta BUGIANESI, 227262
The NLRP3 antagonist IFM-514 decreases fibrosis and inflammation in two mousemodels of non-alcoholic steatohepatitis (NASH)
EASL LiverTree™, Fernando Magdaleno Verduzco, 226648
Human PNPLA3 I148M gene variant impairs secretion of polyunsaturated VLDL-TG and resembles the catalytically inactive PNPLA3 variant in mice
EASL LiverTree™, Panu Luukkonen, 226647
Activating the Hormonal Effect of miR-122 Reverses NASH
EASL LiverTree™, Chofit Chai, 226646
Effect of sebelipase alfa on liver parameters over 96 weeks in a diverse population of children and adults with lysosomal acid lipase deficiency
EASL LiverTree™, Florian Abel, 226645
Round-table discussion & Consensus Statement I: - Assessing patient symptoms in NASH in trial and in practice
EASL LiverTree™, Faculty / Presenter(s), 231715
Patient Reported Outcome Measures - the regulatory perspective
EASL LiverTree™, Elmer Schabel, 227255
Role of patient organizations in progression from NAFLD to NASH and further
EASL LiverTree™, Marko Korenjak, 227254
Patient reported outcome measures in NASH and science behind the symptoms
EASL LiverTree™, Zobair Younossi, 227253
How patients feel: Assessing symptoms in patients with NASH: Chair
EASL LiverTree™, Salvador AUGUSTIN, 227251
Sheep as a large animal model for fatty liver research
EASL LiverTree™, Hay Dvir, 226691
The effect of carvedilol compared to propranolol to control hepatic venous pressure gradient (HVPG) in cirrhotic patients with portal hypertension: an evident based case report
EASL LiverTree™, Afifa Fahriyani, 226692
Association between NAFLD, cardiovascular complications, insulin resistance in obese patiens
EASL LiverTree™, Iryna FEDZHAGA, 226693
Histidine rich glycoprotein as a hypoxia-induciblefactor 2α – dependent pro-fibrogenic mediator in experimental non-alcoholicfatty liver disease.
EASL LiverTree™, Beatrice Foglia, 226694
Automated quantitation of ballooning, inflammation, steatosis and fibrosis using machine learning in routine histological images of liver biopsies of patients with NAFLD
EASL LiverTree™, Roberta Forlano, 226695
Pharmacological inhibition of Adipose Triglyceride Lipase prevents metabolic disorders in mice
EASL LiverTree™, Gernot Grabner, 226696
Human induced pluripotent stem cell derived hepatocyte like cells - a valuable model for drug testing in Nonalcoholic Fatty Liver Disease
EASL LiverTree™, Nina Graffmann, 226697
C-MYC overexpression in hepatocytes is responsible for the spontaneous development of murine non-alcoholic steatopatitis
EASL LiverTree™, Feifei Guo, 226698
Hepatocyte-specific caveolin-1 in non-alcoholic steatohepatitis mouse models.
EASL LiverTree™, Mei Han, 226699
The association between visceral fat and evolution of patients with nonalcoholic fatty liver disease
EASL LiverTree™, Marta Hernandez Conde, 226700
Combination of GLP-1 agonist and SGLT2-inhibitor improves the non-alcoholic steatohepatitis in a high fat-high fructose mice model for NASH
EASL LiverTree™, Katharina Luise Hupa, 226701
Steatotic zebrafish larva to evaluate mechanisms involved in NAFLD progression induced by a mixture of alcohol with an environmental pollutant, benzo[a]pyrene
EASL LiverTree™, Muhammad Imran, 226702
Restoration of Mitochondrial Respiratory Chain Activity by RIP3 Depletion in Experimental NAFLD
EASL LiverTree™, Tawhidul Islam, 226703
State-of-the-art: Carcinogenesis in NASH
EASL LiverTree™, Jessica Zucman-Rossi, 227250
Best animal models for NASH research - view from industry
EASL LiverTree™, Keld Fosgerau, 227249
Mechanisms of fibrogenesis in NASH
EASL LiverTree™, Detlef SCHUPPAN, 227248
Gut and the liver
EASL LiverTree™, Herbert Tilg, 227247
Insulin resistance and lipotoxicity
EASL LiverTree™, Amalia Gastaldelli, 227246
Cumulative effects of Western diet and alcohol abuse: a novel experimental mouse model of NASH/ASH-derived liver injury
EASL LiverTree™, Raquel Benedé, 226677
Multiplex real-time PCR detection of variants in the PNPLA3 and TM6SF2 genes associated with non-alcoholic fatty liver disease
EASL LiverTree™, Anne Berndt, 226678
Genetic assessment of the role of bile acids in children affected by non-alcoholic fatty liver disease
EASL LiverTree™, Teresa Brunetti, 226679
An open label randomized controlled trial of Vitamin D vs Pentoxifylline in non-diabetic patients of Nonalcoholic fatty liver disease
EASL LiverTree™, Sanchit Budhiraja, 226680
An Integrated Primary and Secondary Care Algorithm for Evaluating Non-Alcoholic Fatty Liver Disease Significantly Increases Community Screening for Hepatitis B and C Infection
EASL LiverTree™, Richard J Aspinall, 226681
Who cares about NASH? Patients with NAFLD care!
EASL LiverTree™, Koya Ayonrinde, 226682
Multi-parametric MRI as a composite biomarker for NASH and NASH with fibrosis
EASL LiverTree™, Velicia Bachtiar, 226683
RIPK3-MLKL mediated necroptosis contributes to ischaemia induced cell death in steatotic hepatocytes
EASL LiverTree™, RAJI BAIDYA, 226684
Energy metabolism in obesity reveals that NASH requires targeting AMPK/mTOR-driven pathways
EASL LiverTree™, Noemí Cabré, 226685
Exercise improves HFD-mediated metabolic syndrome, dysbiosis and associated gut-liveraxis and biliar acid deregulation in an in vivo model of early obesity and NAFLD
EASL LiverTree™, Sara Carbajo-Pescador, 226686
The Zucker Diabetic Sprague Dawley rat: a novel model for Type 2 diabetes-related non-alcoholic steatohepatitis
EASL LiverTree™, Rachael Dangarembizi, 226687
Ultrasound-based quantitative assessment of hepatic fat content: the Seato-score system
EASL LiverTree™, Nicole Di Lascio, 226688
Changes in liver fatty acid delta-9, delta-6 and delta-5 desaturase activities in two animal models of hepatic steatosis
EASL LiverTree™, Laura Giuseppina Di Pasqua, 226689
The deletion of perforin protects from non-alcoholic steatohepatitis (NASH) development
EASL LiverTree™, Hannah Drescher, 226690
Effect of Silybin onfibrogenesisin an in vitro model of NASH
EASL LiverTree™, Beatrice Anfuso, 226663
Dietary wheat amylase trypsin inhibitors worsen chronic liver disease in pre-clinical models of NASH and liver fibrosis
EASL LiverTree™, Muhammad Ashfaq Khan, 226664
Does oleuropeininduce apoptosisor autophagic processes in HFD mice?
EASL LiverTree™, Clara Balsano, 226665
Lean versus overweight/obese non-alcoholic fatty liver disease - a clinicopathological comparative study
EASL LiverTree™, Sanchit Budhiraja, 226666
Liver microcirculation disorders and its correction by Hepa-Merz at the nonalcoholic steatohepatitis.
EASL LiverTree™, Tatiana Ermolova, 226667
Clinical impact of comorbidities in NAFLD patients referred in a tertiary centre in Italy
EASL LiverTree™, Antonio Liguori, 226669
Algorithm to identify patients with an activity grade >2 in type 2 diabetic patients with non-alcoholic fatty liver disease (NAFLD) Development in a large prospective multicenter UK study
EASL LiverTree™, Philip N Newsome, 226670
DGAT2 inhibition improves endpoints associated with NASH pre-clinically
EASL LiverTree™, Trenton Ross, 226671
Hypercoagulopathy risk factors in liver cirrhosis patients dueto non-alcoholic steatohepatitis
EASL LiverTree™, Nataliya Virstyuk, 226673
Non-alcoholic steatohepatitis: an independent risk factor for albuminuria in non-diabetic patients
EASL LiverTree™, Ming-Hua Zheng, 226674
Prevalence of de novo metabolic syndrome and its risk factors in a liver transplanted population: a prospective study
EASL LiverTree™, Chiara Becchetti, 226676
An obese mouse model of diet-induced NASH with biopsy-confirmed advanced fibrosis and progressive tumor development
EASL LiverTree™, Michael Feigh, 230985
Promises and limits of non-invasive methods in NASH
EASL LiverTree™, Jérôme Boursier, 227241
Clinical Case II - evolution of identified case + use of non-invasive modalities
EASL LiverTree™, Emmanuel Tsochatzis, 227240
Case identification in diabetes clinics : where do we stand so far ?
EASL LiverTree™, Roy Taylor, 227239
Clinical Case I - how do cases present in the community+ Exemplar case illustrating challenge how to decide which patients need specialist input
EASL LiverTree™, Emmanuel Tsochatzis, 227238
Anti-fibrotic properties of OCA and INT-767 in an in vitro model of NASH
EASL LiverTree™, Beatrice Anfuso, 226649
Deletion of IL-4 Receptor alpha on macrophages attenuates inflammation and fibrosis in murine nonalcoholic steatohepatitis (NASH)
EASL LiverTree™, Muhammad Ashfaq Khan, 226650
HFD mouse model displays altered copper-related gene expression
EASL LiverTree™, Clara Balsano, 226651
Cytokeratin 18 fragment level is a useful biomarker in predicting steatosis and NASH but not fibrosis
EASL LiverTree™, Sanchit Budhiraja, 226652
Endothelial disfunction as a mechanism of the hepatic microcirculation disorders and its correction at the nonalcoholic steatohepatitis patients.
EASL LiverTree™, Tatiana Ermolova, 226653
Genetic susceptibility to increased intestinal permeability is associated with diabetes and progressive liver disease in patients with non-alcoholic fatty liver disease (NAFLD)
EASL LiverTree™, Antonio Liguori, 226655
Comparison of FS3 with different biomarkers to identify patients with active NASH (NAS>=4) and advandced fibrosis (F>=2)
EASL LiverTree™, Philip N Newsome, 226656
ACCi / DGAT2i combination therapy for the treatment of NASH
EASL LiverTree™, Trenton Ross, 226657
Effects of Pioglitazone and L-ornithine-L-aspartate Long Therapy on NASH course in Patients with Diabetes Mellitus Type 2
EASL LiverTree™, Nataliya Virstyuk, 226659
Development of a novel nomogram to detect significant liver fibrosis in biopsy-proven non-alcoholic fatty liver disease
EASL LiverTree™, Ming-Hua Zheng, 226660
A Gut Hormone Can Play A Role in NAFLD
EASL LiverTree™, Mohamed Abdel-Samiee, 226661
Increased liver expression of Vitamin D Receptor is associated with NAFLD, visceral obesity and adipose tissue inflammation
EASL LiverTree™, Ilaria Barchetta, 226662
The clinical picture of NAFLD/NASH: Round-table discussion
EASL LiverTree™, Faculty / Presenter(s), 227235
The current policy on NAFLD in Europe - results from the EILF NAFLD policy review
EASL LiverTree™, Frank Tacke, 227234
Natural history and use of large data to risk stratify
EASL LiverTree™, Quentin Mark Anstee, 227233
Paediatric NAFLD: the future burden of NASH including the risk of HCC linked to obesity during childhood
EASL LiverTree™, Valerio Nobili, 227232
Health care burden of NAFLD and NASH
EASL LiverTree™, Jacob George, 227231
Global overview of obesity and population strategies to tackle it
EASL LiverTree™, Harry Rutter, 227230
Welcome and introductory remarks
EASL LiverTree™, Prof. Frank Tacke & Philip N. Newsome, 233814
From the Editor’s desk....
EASL LiverTree™, Richard Moreau, 234451
JHEP at a glance (September 2018)
EASL LiverTree™, Journal of Hepatology, 234452
Low subcutaneous adiposity associates with higher mortality in female patients with cirrhosis
EASL LiverTree™, Aldo J. Montano-Loza, 234462
Class III obesity is a risk factor for the development of acute-on-chronic liver failure in patients with decompensated cirrhosis
EASL LiverTree™, Vinay Sundaram, 234463
Molecular profiling of subclinical inflammatory lesions in long-term surviving adult liver transplant recipients
EASL LiverTree™, Alberto Sanchez-Fueyo, 234464
Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis
EASL LiverTree™, Amedeo Columbano, 234465
The P2X4 purinergic receptor regulates hepatic myofibroblast activation during liver fibrogenesis
EASL LiverTree™, José Ursic Bedoya, 234466
Human liver infiltrating γδ T cells are composed of clonally expanded circulating and tissue-resident populations
EASL LiverTree™, Benjamin E. Willcox, 234467
JNK1 induces hedgehog signaling from stellate cells to accelerate liver regeneration in mice
EASL LiverTree™, Pierre-Alain Clavien, 234468
Influence of ablation technique on treatment failure for perivascular hepatocellular carcinoma
EASL LiverTree™, Jean-Yves Mabrut, 234478
Reply to: “Influence of ablation technique on treatment failure for perivascular hepatocellular carcinoma”
EASL LiverTree™, Tae Wook Kang, 234479
Protective effects of heme oxygenase 1 during ischemia-reperfusion injury: Hepatocytes or non-parenchymal cells?
EASL LiverTree™, Qiang Xia, 234480
Reply to: “Protective effects of heme oxygenase 1 during ischemia-reperfusion injury: Hepatocytes or non parenchymal cells?”
EASL LiverTree™, Jerzy Kupiec-Weglinski, 234481
Imaging endpoints for non-alcoholic steatohepatitis (NASH) therapeutic trials: A growing role for multiparametric MRI?
EASL LiverTree™, Matt Kelly, 234482
Is obesity a risk factor for the development of acute-on-chronic liver failure in patients with decompensated cirrhosis?
EASL LiverTree™, Tian Yang, 234483

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